Napalolides A−D, Four New Sesquiterpene Lactones from Carpesium nepalense

Four new germacranolide sesquiterpenes, nepalolides A (2), B (3), C (4), and D (5a), and one known germacranolide, ineupatorolide A (1), were isolated from Carpesium nepalense. The structures of these new compounds were elucidated from spectral evidence and chemical transformation.