Mechanical and numerical investigations of biodegradable magnesium alloy screws for fracture treatment

材料科学 弯曲 还原(数学) 镁合金 流离失所(心理学) 钛合金 吸收 生物力学 断裂(地质) 材料性能 复合材料 口腔正畸科 合金 医学 几何学 数学 生理学 病理 心理学 心理治疗师
作者
Sabrina Söntgen,Ludger Keilig,Koroush Kabir,Anna Weber,Susanne Reimann,Kristian Welle,Christoph Bourauel
出处
期刊:Journal of Biomedical Materials Research Part B [Wiley]
卷期号:111 (1): 7-15 被引量:10
标识
DOI:10.1002/jbm.b.35127
摘要

Abstract Small fracture treatment includes the use of so‐called “Herbert screws”. In the past years, novel resorbable materials were introduced as an alternative to the classical titanium implants. The purpose of this study was to evaluate the influence of ongoing resorption/corrosion processes on the mechanical stability screws made from the magnesium alloy MgYREZr®. Our samples consisted of two partly resorbed screws, explanted due to medical reasons after 6 and 12 weeks, respectively, and five unused reference screws. We performed three‐point bending tests to determine the stability of all screws. Additionally, with FE‐models of the screws based on μCT‐scans, we investigated whether any differences in the bending behavior of the screws can be attributed to the reduction of the material volume due to resorption alone. Both partly resorbed screws failed at a lower force than the reference screws (178.6 ± 5.5 N for the reference screws, 72.5 N and 74.5 N for the screw explanted after 6 and 12 weeks, respectively). FE simulations performed with the three different geometries and original material parameters (Young's modulus E new = 45 GPa, yield limit σ new = 235 MPa) showed that the early fracture could not be attributed to the changed geometry alone. Material parameters for the partly resorbed screws were determined by fitting the numerical to the experimental force‐displacement curves ( E 6week = 15 GPa, σ 6week = 135 MPa and E 12week = 8 GPa, σ 12week = 135 MPa, respectively). Our results showed that both geometry of the screws and different material properties contribute to the overall stability. Understanding and controlling these two factors throughout the resorption process could enhance treatment options.
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