医学
来氟米特
内科学
荟萃分析
狼疮性肾炎
蛋白尿
肌酐
环磷酰胺
不利影响
科克伦图书馆
肾功能
随机对照试验
贾达德量表
系统性红斑狼疮
胃肠病学
化疗
疾病
肾
甲氨蝶呤
作者
Heng Cao,Yuefeng Rao,Lin Liu,Jin Lin,Hongyu Yang,Xingguo Zhang,Zhong Chen
出处
期刊:PLOS ONE
[Public Library of Science]
日期:2015-12-15
卷期号:10 (12): e0144548-e0144548
被引量:41
标识
DOI:10.1371/journal.pone.0144548
摘要
Leflunomide is a promising therapy for LN treatment, primarily because of the comparable efficacy and favorable safety profile determined by this meta-analysis of RCTs. Larger RCTs with longer duration of observation are necessary to provide strong evidence of the efficacy and safety of leflunomide in LN patients.
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