Clinical effect of etanercept on juvenile idiopathic arthritis

Objective To observe the clinical effect of etanercept on juvenile idiopathic arthritis.Methods 32 cases of patients with juvenile idiopathic arthritis were selected and treated by etanercept subcutaneous injection 0.4 mg·kg-1),twice a week.The symptoms,laboratory index and adverse effect were observed.Results Six months after the treatment by etanercept,the dosage of prednisone were reduced and eight cases stopped taking prednisone.The values of WBC,ESR,CRP and SF were reduced significantly(P0.01).The number of involved joint was reduced from(6.5±1.2) to(1.4±0.3).There was no serious adverse effect in the treatment.Conclusion The clinical effect of etanercept on juvenile idiopathic arthritis is significant and the incidence of adverse effect is low.It is worthy of generalization.