The effectiveness of 100 mg aspirin in preventing superimposed preeclampsia in women with chronic hypertension: a real-world study

Our study suggests that initiating 100 mg/day of aspirin between 12 and 20 weeks of gestation does not significantly reduce superimposed PE in women with CHTN; however, it significantly reduces the risk of SGA. Subgroup analyses also indicated that even initiation before 16 weeks did not provide additional preventive effect against PE.