Application of low-dose vasopressin in the management of septic shock

A number of recent reports suggest that vasopressin may improve organ perfusion and contribute usefully to the cardiovascular management of septic shock. The rationale for the use of vasopressin is its relative deficiency of plasma levels and hypersensitivity to its vasopressor effects during septic shock. Although it is being used more frequently, there are no randomized clinical trials comparing vasopressin as a first-line vasopressor. Key words: septic shock ;  vasopressin;  vasoconstrictor agents