医学
安慰剂
血清转化
血清流行率
单纯疱疹病毒
随机对照试验
内科学
接种疫苗
免疫
免疫学
疫苗效力
病毒学
抗体
病毒
血清学
病理
替代医学
作者
Lawrence Corey,Andria Langenberg,Rhoda L. Ashley,Rose E. Sekulovich,Allen Izu,John M. Douglas,H. Hunter Handsfield,Terri Warren,Lisa Marr,Stephen K. Tyring,Richard P. DiCarlo,Adaora A. Adimora,Peter A. Leone,Cornelia L. Dekker,Rae Lyn Burke,Wai Yie Leong,Stephen E. Straus,for the Chiron HSV Vaccine Study Group
出处
期刊:JAMA
[American Medical Association]
日期:1999-07-28
卷期号:282 (4): 331-40
被引量:477
标识
DOI:10.1001/jama.282.4.331
摘要
Efficient and sustained protection from sexual acquisition of HSV-2 infection will require more than high titers of specific neutralizing antibodies. Protection against sexually transmitted viruses involving exposure over a prolonged period will require a higher degree of vaccine efficacy than that achieved in this study.
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