医学                        
                
                                
                        
                            慢性化脓性中耳炎                        
                
                                
                        
                            鼓室成形术                        
                
                                
                        
                            外科                        
                
                                
                        
                            表皮葡萄球菌                        
                
                                
                        
                            中耳炎                        
                
                                
                        
                            内窥镜                        
                
                                
                        
                            耳鼻咽喉科                        
                
                                
                        
                            金黄色葡萄球菌                        
                
                                
                        
                            细菌                        
                
                                
                        
                            遗传学                        
                
                                
                        
                            生物                        
                
                        
                    
            作者
            
                Linglan Gu,Yuhui Deng,Ying Zhou,Wuqing Wang,Dongdong Ren,Jianghong Xu            
         
                    
        
    
            
            标识
            
                                    DOI:10.1177/01455613241300891
                                    
                                
                                 
         
        
                
            摘要
            
            Objective: To analyze the clinical effect of tympanoplasty performed for chronic suppurative otitis media (CSOM) patients with otomycosis under the oto-endoscope. Methods: A retrospective analysis was conducted on the healing of the tympanic membrane and hearing improvement of 431 CSOM patients who underwent endoscopic type 1 tympanoplasty. The patients with CSOM were divided into the control group ( n = 203, without otomycosis) and the trial group ( n = 184, with otomycosis). The patients were followed up for at least 3 months. The graft uptake rate and hearing improvement were compared. Results: The graft uptake rate was 94.57% (174/184) in the trial group and 96.06% (195/203) in the control group, indicating no significant difference between the 2 groups. The preoperative and postoperative average air-conduction hearing thresholds of CSOM with otomycosis were 42.68 ± 11.46 dBHL and 33.01 ± 11.51 dBHL, respectively ( P = .000). Mean air-bone gap (ABG) reduction values were 3.96 ± 7.20 dBHL and 3.34 ± 7.96 dBHL, respectively. There was no significant difference in the average ABG ( P = .420) and average air-conduction hearing threshold ( P = .649) between the trial group and the control group after operation. The culture results of the CSOM group with otomycosis showed that the most common fungal genus was Aspergillus (87/173), with 32 cases of mixed infection of fungi and bacteria, and the most common mixed infection of bacteria was Staphylococcus epidermidis (9/32). The failure graft uptake was noticed in 8.8% (5/57) cases in the trial group with postoperative fungal infection and 3.9% (5/127) without otomycosis ( P = .289). No significant difference was found in the successful healing rate among age, duration, perforation size, fungal type, postoperative fungal infection. Conclusion: CSOM with otomycosis is not a contraindication for endoscopic type 1 tympanoplasty, and external auditory canal fungal infection does not affect postoperative healing and hearing improvement. Intraoperative repeated rinsing with povidone-iodine may reduce the occurrence of postoperative infection.
         
            
 
                 
                
                    
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