Effectiveness of Chinese Herbal Medicine in Patients with COVID-19 During the Omicron Wave in Hong Kong: A Retrospective Case-Controlled Study

四分位间距 医学 2019年冠状病毒病(COVID-19) 内科学 中医药 爆发 传统医学 严重急性呼吸综合征冠状病毒2型(SARS-CoV-2) 胃肠病学 替代医学 病毒学 疾病 病理 传染病(医学专业)
作者
Jialing Zhang,Jingyuan Luo,Hiu To Tang,Hoi Ki Wong,Yanfang Ma,Duoli Xie,Bo Peng,Aiping Lyu,Chun Hoi Cheung,Zhaoxiang Bian
出处
期刊:The American Journal of Chinese Medicine [World Scientific]
卷期号:51 (07): 1615-1626
标识
DOI:10.1142/s0192415x23500738
摘要

SARS-CoV-2 Omicron led to the most serious outbreak of COVID-19 in Hong Kong in 2022. Under the pressure of a high volume of patients and limited medical resources, Chinese herbal medicine (CHM) has been extensively used. This is a case-control study of the infected patients that aims to evaluate the effectiveness of CHM using data extracted from the Hong Kong Baptist University Telemedicine Chinese Medicine Centre database. Patients with COVID-19 confirmed by either a rapid antigen test or a polymerase chain reaction who had completed two consultations and taken CHM within 10 days of the first positive test were included in the study (CHM group, [Formula: see text]). The matched control cases were those who did not take CHM within 10 days of the first positive test and were based on age ([Formula: see text] 3 years), vaccine doses ([Formula: see text] 3 doses, or 3 doses), and gender (no-CHM group, [Formula: see text]). The outcomes included the negative conversion time (NCT, primary outcome), total score of individual symptoms, number of the reported symptoms, and individual symptom disappearance rates. The NCT of the CHM group (median days: 7.0, interquartile range: 6.0–8.0) was significantly shorter than that of the no-CHM group (8.0, 7.0–10.5; [Formula: see text]). CHM treatment significantly reduced the total score of individual symptoms ([Formula: see text]) and the number of the reported symptoms ([Formula: see text]) as compared with that of the no-CHM group. Additionally, the symptom disappearance rates of symptoms such as chills, cough, sputum, dry throat, itching throat, headache, chest tightness, abdominal pain, diarrhea, and fatigue were significantly higher in the CHM group than in the no-CHM group. In conclusion, CHM intervention can significantly reduce NCT and COVID-19 symptoms. Chinese medicine can be accurately prescribed based on a telemedical consultation.
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