医学
肾细胞癌
PET-CT
核医学
Pet成像
成纤维细胞活化蛋白
正电子发射断层摄影术
病理
癌症
内科学
作者
Rong Lin,Chao Wang,Fuqi Xu,Jie Zang,Weibing Miao
出处
期刊:Clinical Nuclear Medicine
[Ovid Technologies (Wolters Kluwer)]
日期:2023-10-07
卷期号:48 (12): 1119-1121
标识
DOI:10.1097/rlu.0000000000004881
摘要
Abstract A 57-year-old man was incidentally found with 3 lesions located in bilateral kidneys, which were finally diagnosed as renal cell carcinoma (RCC) by postoperative pathology. 68 Ga-LNC-1007, also denoted as 68 Ga-FAPI-RGD, was synthesized from fibroblast activation protein inhibitor-02 (FAPI-02) and cyclic arginine-glycine-aspartate (RGD), which could target both FAP and integrin α v β 3 . RCC lesions demonstrated only slight 68 Ga-PSMA uptake, but intense tracer uptake on 68 Ga-LNC-1007 PET/CT. This case demonstrates the potential value of 68 Ga-LNC-1007 PET/CT for the evaluation of RCC.
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