Reduced Capacity of High‐Density Lipoprotein to Acquire Free Cholesterol From Triglyceride‐Rich Lipoproteins Is Associated With Elevated Postprandial Hypertriglyceridemia in Healthy Men

The capacity of high-density lipoprotein cholesterol (HDL) to acquire free cholesterol (FC) from triglyceride-rich lipoproteins during lipoprotein lipase-dependent lipolysis in a process of reverse remnant cholesterol transport, has been proposed as a key biological function of HDL particles that underlies the U-shaped relationship between HDLcholesterol and cardiovascular diseases. Although reverse remnant cholesterol transport has been evaluated in a fasting state, it has never been explored under nonfasting conditions.