Prevalence and comorbidity burden of prurigo nodularis in United States adults enrolled in the All of Us research program

To the Editor: Prurigo nodularis (PN) is a chronic inflammatory skin condition characterized by intensely pruritic nodules on the extensor surfaces of extremities and on the trunk. 1 Kwatra S.G. Breaking the itch-scratch cycle in prurigo nodularis. N Engl J Med. 2020; 382: 757-758https://doi.org/10.1056/NEJMe1916733 Crossref PubMed Scopus (37) Google Scholar The prevalence of PN remains poorly characterized. To further understand the epidemiology of PN, our study estimated the prevalence of PN and characterized comorbidity burden in PN patients using data from All of Us, a National Institute of Health database containing health information from US adults.