Liquid Metal: A New Approach to Diagnosis and Treatment of Cardiovascular Diseases

Cardiovascular diseases (CVDs) remains a leading cause of high mortality and imposes a significant health burden globally. The biocompatibility between materials and the cardiovascular system, encompassing biological safety, modulus matching, and anti-fatigue performance in dynamic physiological environments, has been a critical challenge in the diagnosis and treatment of CVDs. The emergence of liquid metal (LM) offers promising opportunities to develop diagnostic and therapeutic methods that exhibit excellent biocompatibility with the cardiovascular system. In this perspective, the progress of LM applications in contrast agents, nanomedicine, implantable and wearable bioelectronic devices, and bionic materials is evaluated, providing a comprehensive and in-depth discussion of the role and advantages of LM in CVDs management. Finally, the current challenges and future prospects of LM in the field of CVDs diagnosis and treatment are outlined.