Recent progress in assembly strategies of nanomaterials-based ultrasensitive electrochemiluminescence biosensors for food safety and disease diagnosis

The Electrochemiluminescence (ECL)-based biosensors have received considerable attention in food contaminants and disease diagnosis, due to their fascinating advantages such as low cost, fast analysis speed, wide linear range, high sensitivity, and excellent anti-interference ability. Meanwhile, with the vigorous development and improvement of nanotechnology, biosensor assembly strategies tend to diversify and be multifunctional. This review focuses on the representative ECL biosensors in food safety and disease diagnosis reported by our research group and other research groups based on nanomaterials assembly strategies in recent years. According to the different roles of nanomaterials played in the constitution of ECL biosensors, nanomaterials would be divided into the following two categories to be summarized: (1) Nanomaterials for signal amplification. (2) Nanomaterials as ECL emitters. Finally, this review prospects the perspectives on the future development direction of ECL biosensor in food safety and disease diagnosis.