Magnetic Nanoparticle-Based Biosensors for the Sensitive and Selective Detection of Urine Glucose

In this work, a diagnostic application was performed by utilizing magnetic nanoparticles for the bio-sensing. A novel Fe 3 O 4 nanostructure was synthesized in this paper using a simple hydrothermal method, the Fe 3 O 4 nanoparticles are successfully controlled to provide a more dynamic site for catalytic reaction. FTIR-analysis, scanning electron microscopy (SEM), X-ray diffraction (XRD) was used to examine the morphology of the synthesized nanoparticles. The findings showed that a unique Fe 3 O 4 nanostructure was obtained nanoparticles confined in nanosphere. The relative catalytic kinetics of Fe 3 O 4 nanostructure has followed Michaelis–Menten behaviours, according to an analysis of peroxidase-like activity. An effective approach for colorimetric sensing of glucose was formulated on the bases of efficient peroxidase-mimicking activity of Fe 3 O 4 nanoparticles. The synthesized Fe 3 O 4 nanoparticles are very hopeful for the application of bio-sensors.