An unexpected transition-metal free regioselective cyclization of alkynyl-tethered indoles to prepare indole-fused azepino[2,1- b ]quinazolinones and spiroindole-pyrrolo[2,1- b ]quinazolinones

A base-promoted atom economical and unexpectedly selective cyclization strategy was developed for the synthesis of indole-fused azepino[2,1- b ]quinazolinones and spiroindole-pyrrolo[2,1- b ]quinazolinones.