Copper‐Catalyzed CH Functionalization Intermediates and Mechanisms

Abstract CH functionalization reactions enable the efficient introduction of functionality in place of ubiquitous CH bonds. In particular, copper catalysts have seen rapid development and synthetic applications in recent years due, in part, to their ability to easily access multiple oxidation states and intermediates in varied mechanistic pathways. In this article, the predominant mechanistic intermediates and manifolds for Cu‐catalyzed CH activation reactions are presented.