脂肪酶
发酵
脱脂牛奶
食品科学
乳酸
细菌
化学
水解
生物化学
脂蛋白脂酶
酶
生物
遗传学
作者
Ana María Gil-Rodríguez,Tom Beresford
标识
DOI:10.1016/j.jff.2020.104342
摘要
Obesity is the main cause of metabolic syndrome, a condition of which includes hypercholesterolemia. Reduced dietary fat absorption through inhibition of pancreatic lipase and/or hydrolysis of bile salts may provoke weight loss and cholesterol reduction. In this study, the potential anti-obesity properties of milk fermented with lactic acid bacteria was assessed by measuring the expression of bile salt hydrolase (BSH) after milk fermentation and the ability of fermentates to inhibit pancreatic lipase in vitro. Thirty BSH positive strains were identified, with 17 strains expressing this enzyme during milk fermentation. Apart from BSH activity, the milks fermented with L. plantarum SC70 and SC80 also displayed the capacity to inhibit pancreatic lipase by >35%. As expression of BSH and inhibition of pancreatic lipase are proposed synergistic activities to reduce fat absorption, fermentates produced with these strains are good candidates for use as functional foods for the treatment of obesity and hypercholesterolemia.
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