Copper‐Catalyzed C – H Activation

Transition-metal-catalyzed C–H activation has become a powerful strategy in organic synthesis because the direct C–H functionalization can construct complex compounds from simple starting materials with high atom economy. This chapter aims to describe the advances on Cu-catalyzed C–H activation. These results are organized into carbon–carbon bond formation and carbon–heteroatom bond formation according to the type of the bond formation. The section of carbon–carbon bond formation is divided into C(sp2)–H activation and C(sp3)–H activation based on the type of C—H bond, and the section of carbon–heteroatom bond formation is separated into C—N, C—O, C—X, C—P, and C—S according to the different heteroatoms involved in the bond formation. With the continuous research by organic chemists in this field, novel reactions via copper-catalyzed C–H activation will increasingly emerge.