An overview of poly (amide-amine) dendrimers functionalized chromatographic separation materials

Chromatography is one of the most important separation techniques in analytical chemistry. In which, the separation materials are the core for good separation results. Poly (amide-amine) dendrimers with regular three-dimensional structure, abundant terminal groups, controllable molecule chains, and unique cavities appear to have a positive impact on chromatographic separation materials. In the past decades, poly (amide-amine) grafted adsorbents and stationary phases have presented high grafting efficiency, controllable surface structure, good dispersion, and wide practical applications. In this review, the prepared poly (amide-amine) functionalized separation materials and their applications are systematically summarized. Functions, significance, structure-actvity relationships and benefits of poly (amide-amine) dendrimers in the proposed separation materials are discussed in detail. And we hope to provide a useful reference for the future development of chromatographic separation materials and inspire new discoveries in the study of poly (amide-amine) functionalized materials.