谵妄
认知功能衰退
医学
认知障碍
术后认知功能障碍
疾病
生物标志物
痴呆
认知
心脏外科
执行功能障碍
重症监护医学
老年学
心脏病学
精神科
内科学
神经心理学
化学
生物化学
作者
Tina B. McKay,Jason Z. Qu,Feng Liang,Ariel Mueller,Jeanine P. Wiener-Kronish,Zhongcong Xie,Oluwaseun Akeju
标识
DOI:10.1016/j.bja.2022.04.002
摘要
Editor-Neurologic dysfunction following major cardiac surgery is characterized by a decline in memory and executive function.1 This cognitive decline, which approximates Alzheimer's Disease and Related Dementias (ADRD), is evident at hospital discharge, followed by early improvement at six months, and worsening at five years.1 Worse, the cognitive decline associated with patients who develop postoperative delirium is accelerated.2 Recent studies suggest underlying patient vulnerabilities contribute to delirium.
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