This article, by means of biological toxicity tests, analyzes the feature of the bottom sediment poison pollution in the Dashahe River. Results show as follows: The Dashahe River bottom sediment has been to a different degree. The tendency of the bottom sediment poison pollution is essentially the same as that of the water body poison pollution. Besides, this article, with chemistry monitoring means, analyzes that the poison in the bottom sediment is mostly organic matter. Moreover, it proposes views and ideas of administrating the Dashahe bottom sediment poison pollution.