Inhibitory effect of FFYC tablets(FFYC) on expression of HBsAg and HBeAg

Objective: To study the inhibitory effect of FFYC tablets (FFYC) on expression of HBeAg and HBsAg. Methods: The 2.2.15 cell line was cultured with cell cultured medium including different concentration of FFYC. By means of radioimmunoassay, the hepatitis B surface antigen ( HBsAg) and hepatitis B e antigen (HBeAg) were examined. Results: The max cytotoxicity concentration of FFYC was 600g/mL. Based on this concentration, FFYC was diluted and was added in cell culture medium. The results showed that HBeAg, HBsAg values of 2.2.15 cells treated by FFYC were lower than those in the control. Conclusion: FFYC could inhibit HBV replication and expression.