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Posttraumatic stress disorder after second-trimester medical termination of pregnancy

医学 孕中期 创伤后应激 怀孕 产科 终止妊娠 风险因素 妇科 相对风险 梅德林 妊娠期 风险评估 产妇发病率 精神科
作者
O. Anselem,A.J. Vivanti,H. Bouchghoul,T. Quibel,N. Winer,JM Jouannic,V. Castaigne,E. Perdriolle-Galet,J. Massardier,J. Rousseau,Radjack Rahmethnissah,V. Tsatsaris,P.Y. Ancel,F. Goffinet,O. Anselem,V. Tsatsaris,F. Goffinet,JM Jouannic,L. Guilbaud,N. Winer
出处
期刊:American Journal of Obstetrics and Gynecology [Elsevier BV]
卷期号:235 (1): 205-213 被引量:1
标识
DOI:10.1016/j.ajog.2026.02.021
摘要

OBJECTIVE: To evaluate the risk of posttraumatic stress disorder after indicated second-trimester termination of pregnancy and to identify factors associated with a probable diagnosis of severe posttraumatic stress disorder. STUDY DESIGN: weeks of gestation. Posttraumatic stress disorder was evaluated by the Impact of Event Scale-Revised questionnaire, self-administered 1 to 4 months after termination of pregnancy. This 22-item scale is designed to assess subjective distress caused by traumatic events and has been validated in perinatal care. The literature suggests that a score ≥33 indicates a probable diagnosis of posttraumatic stress disorder and a score ≥37 a probable diagnosis of severe posttraumatic stress disorder. Maternal and obstetric characteristics associated with a score ≥37 were studied with mixed models. We present results after multiple imputation to take selective dropouts and missing information at follow-up into account and for complete cases. RESULTS: Among the 347 women enrolled, 247 (71.2%) Impact of Event Scale-Revised questionnaires were available. Median time between termination of pregnancy and completion of the questionnaire was 7 weeks (interquartile range, 4.9-13.3). The mean Impact of Event Scale-Revised score was 32.1 (standard deviation, 15.4). The Impact of Event Scale-Revised score was ≥33 for 44.9% (95% confidence interval, 38.4-51.4) of women and ≥37 for 35.8% (95% confidence interval, 29.7-41.8). After multivariate analysis, obstetric or labor-related characteristics such as parity, gestational age over 22 weeks, use of cervical dilators, labor >12 hours, and pain or complications during delivery or postpartum were not associated with an Impact of Event Scale-Revised score ≥37. The results were similar in complete cases. CONCLUSION: Nearly half of women undergoing medically indicated second-trimester termination of pregnancy were at risk of posttraumatic stress disorder and more than one-third of severe posttraumatic stress disorder. The absence of risk factors underlines the potential benefits of systematic psychological evaluation after termination of pregnancy for all women.

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