The hawthorn ( Crataegus pinnatifida ) procyanidin extract attenuates nonalcoholic fatty liver disease in mice via remodeling the bile acid profile driven by gut microbiota and regulating the FXR pathway

Hawthorn procyanidin extract (HPC) is one of natural plant-derived polyphenol with lipid-lowering and liver-protective properties, while its therapeutic mechanisms against nonalcoholic fatty liver disease (NAFLD) require further clarification.