REGULATION OF HDL DYSFUNCTIONALITY BY PHOSPHATIDYLETHANOLAMINE LINKS POLY-UNSATURATED FATTY ACIDS WITH ATHEROSCLEROTIC CARDIOVASCULAR DISEASES
作者
Malik Taradeh,Lise M Hardy,Veronica D Dahik,Marie Lhomme,Hua Wang,Canelle Reydellet,Clément Materne,Pukar Kc,Eric Bun,Maud Clemessy,Jean-Paul Pais-de-Barros,Sophie Galier,Eric Frisdal,Herve Durand,Maharajah Ponnaiah,Petra El Khoury,Elise F. Villard,Philippe Lesnik,Antonio Gallo,Laurent Kappeler
This study reveals a causal link between PE species, particularly ARA-PE, and HDL dysfunction, contributing to atherosclerosis. EPA-PE can restore HDL function, supporting the therapeutic potential of EPA reducing ASCVD risk.