Sex Differences in Left Ventricular Remodeling for Risk Stratification of Patients With Aortic Regurgitation

In this study among individuals with moderate-severe AR, similar LVESDi thresholds (20 mm/m2) for both sexes, but lower than currently recommended by guidelines, were independently associated with mortality. In turn, LVESVi thresholds were 40 mL/m2 for women and 45 mL/m2 for men, suggesting the need for sex-specific cutoffs to improve risk stratification.