加替沙星
司帕沙星
化学
抗菌活性
抗菌剂
吡啶
体外
环丙沙星
化学合成
组合化学
立体化学
药物化学
抗生素
细菌
氧氟沙星
生物化学
生物
遗传学
作者
Brijesh Kumar Srivastava,Manish Solanki,Bhupendra Mishra,Rina Soni,Sanjaya Jayadev,Darshan Valani,Mukul R. Jain,Pankaj Patel
标识
DOI：10.1016/j.bmcl.2007.01.038
摘要
Synthesis and antibacterial activity of a number of substituted 4,5,6,7-tetrahydro-thieno[3,2-c]pyridine quinolones is reported. The antibacterial activities were evaluated in standard in vitro MIC assay method. Some of the compounds showed in vitro (MIC) antibacterial activity comparable to those of Gatifloxacin, Ciprofloxacin, and Sparfloxacin.
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