经颅直流电刺激
自闭症谱系障碍
脑刺激
自闭症
神经心理学
心理学
检查表
人口
背外侧前额叶皮质
荟萃分析
临床心理学
物理医学与康复
协议(科学)
前额叶皮质
精神科
医学
神经科学
认知
刺激
认知心理学
替代医学
环境卫生
病理
内科学
作者
Sara García-González,Jorge Lugo‐Marín,Imanol Setien-Ramos,Laura Gisbert-Gustemps,Gara Arteaga‐Henriquez,Emiliano Díez Villoria,Josep Antoni Ramos‐Quiroga
标识
DOI:10.1016/j.euroneuro.2021.02.017
摘要
Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that has gained relevance in recent years as an alternative treatment for neuropsychiatric conditions. The aim of this study is to conduct a systematic review of the use of tDCS in Autism Spectrum Disorder (ASD). Both electronic and manual searches were conducted to identify studies published in peer-reviewed scientific journals addressing the use of tDCS in ASD population. A total of 16 studies fulfilled the criteria to be included in the review. Studies were conducted both in child and adult population. Anodal stimulation on the left dorsolateral prefrontal cortex was the most commonly chosen methodology. Outcomes addressed ASD symptoms and neuropsychological functions. Meta-analytic synthesis identified improvements in social, health, and behavioral problem domains of the Autism Treatment Evaluation Checklist. Limitations included high heterogeneity in the methodology and low-efficacy study designs (pre-post and single-case studies). Recent controlled trials shed promising results for the use of tDCS in ASD. A standardized stimulation protocol and a consensus in the measures used in the evaluation of the efficacy are imperative.
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