嗅觉
疾病
痴呆
背景(考古学)
嗅觉系统
心理学
神经科学
认知
医学
生物
病理
古生物学
作者
Esther Wang,Jayant M. Pinto
出处
期刊:Chemical Senses
[Oxford University Press]
日期:2021-01-01
卷期号:46
被引量:10
标识
DOI:10.1093/chemse/bjab045
摘要
Age-related olfactory dysfunction, or presbyosmia, is a common sensory impairment in aging adults. People in this demographic group with comorbid conditions or exposure to viral, traumatic, or environmental insults remain at the greatest risk for impairment. Several methods for assessing olfaction exist, but they are only available in special settings and require consideration of age, sex, ancestry, and cognition. Perhaps most importantly, olfactory dysfunction has been suggested as an early sign of Alzheimer's and Parkinson's disease and therefore may serve as a tool in the diagnosis and prognosis of these neurodegenerative conditions. Outside of this context, olfactory loss also impacts nutrition, safety, and social relationships, and even predicts mortality itself. This review covers the detection and manifestations of olfactory decline in aging individuals and the myriad ways in which olfactory impairment is connected to their health and well-being.
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