Protective Effect of Orignm vulgara Against UV Irradiation on DNA

This research aimed to study the effects of different radiations sources in the DNA structure, the irradiations used in this study is Ultraviolet and this is as a stimulation model for the Iraqi environment after the long exposure for different weapons in the repeated wars that happened, and chemical pollutants from car exhaust as well as from factories activities.The white blood cells were exposed to Ultraviolet ray for different time intervals. Also we study the effects of Orignm vulgara fractionation organic extract as a protective method for the destructive effects of irradiations by using DNA fragmentation test.The results showed that short time exposure to Ultraviolet ray for (5, 10, 15 min) at (30, 0 cm) highest have no effect on DNA structure, while the exposure to Ultraviolet ray for (3 hour, 0 cm) produce DNA decay. To counteract this destructive effect of irradiation the Orignm vulgara organic extract was added to the cells suspension before irradiation. Key words: UV Irradiation, DNA fragmentation test, fractionation organic extract.