Ricin and Abrin Poisoning

This chapter contains sections titled: Ricin The Potential Use of Ricin as a Chemical Weapon Ricin Structure Ricin Biosynthesis The Substrate for Ricin Mode of Action of Ricin a Chain Binding of Ricin to Mammalian Cells Endocytosis of Ricin Transport of Ricin from Endosomes to the Endoplasmic Reticulum Release of Ricin into the Cytosol Toxicokinetics of Ricin Exposure Clinical Features of Ricin Poisoning Diagnosis of Ricin Poisoning Management of Ricin Poisoning Experimental Strategies for Protecting against Ricin Toxicity Abrin Structure and Mechanisms of Toxicity of Abrin Toxicokinetics of Abrin Exposure Clinical Features of Abrin Exposure Diagnosis Management of Abrin Poisoning Conclusions References