Synthetic Microbial Ecosystems for Stable Flow Biocatalysis

Constructing living materials with microbial consortia represents an emerging approach for creating life-like functional systems; however, the spatiotemporal orchestration of the activities across diverse species remains a major challenge. Yu et al. address this with a 3D-printable hydrogel matrix that embeds phase-separated aqueous microdroplets for microbial compartmentalization, enabling sustained biocatalysis under continuous flow (https://doi.org/10.1002/anov.70015).