A case of endocarditis caused by Microascus trigonosporus

A case of endocarditis caused by Microascus trigonosporus related was reported.The strain was isolated from the pacemaker surface and identified as Microascus trigonosporus by ITS analysis.Histopathology showed abundant septate hyphae and intercalary swollen chlamydospores in the vegetaion.Microascus trigonosporus widely spread in the natural world was anamorphs(asexual forms) of Scopulariopsis.Endocarditis caused by Microascus was rarely reported.Etest showed the MICs of itraconazole and amphotericin B were ≥32 μg/mL,while the MIC of voriconazole was 4 μg/mL.The patient improved by vegetation removal and itroconazole treatment.