幽门螺杆菌
生物传感器
注意事项
纳米技术
背景(考古学)
微流控
计算生物学
计算机科学
生物
医学
材料科学
病理
遗传学
古生物学
作者
Kirti Saxena,Nidhi Chauhan,Utkarsh Jain
标识
DOI:10.1016/j.ab.2021.114325
摘要
Invasive as well as non-invasive conventional techniques for the detection of Helicobacter pylori (H. pylori) have several limitations that are being overcome by the development of novel, rapid and reliable biosensors. Herein, we describe several biosensors fabricated for the detection of H. pylori. This review aims to provide the principles of biosensors and their components including in the context to H. pylori detection. The major biorecognition elements in H. pylori detection include antigen/antibodies, oligonucleotides and enzymes. Furthermore, the review describes the transducers, such as electrochemical, optical and piezoelectric, also including microfluidics approaches. An overview of the biomarkers associated with H. pylori pathogenesis is also discussed. Finally, the prospects of advancement and commercialization of point-of-care tools are summarized.
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