免疫疗法
免疫
肠道菌群
癌症
免疫系统
免疫学
癌症免疫疗法
先天免疫系统
生物
获得性免疫系统
肿瘤免疫学
遗传学
作者
Zhilin Zhang,Yiqun Liao,Dong Tang
出处
期刊:Carcinogenesis
[Oxford University Press]
日期:2022-07-22
卷期号:43 (8): 719-727
被引量:9
标识
DOI:10.1093/carcin/bgac063
摘要
Microbiota-host interactions are a hot topic of research because of their important role in regulating the malignant transformation of cancer cells and cancer-related immunity. The role of gut microbiota, oral microbiota and skin microbiota in cancer progression has been extensively studied. However, intratumoral microbiota is a recently discovered topic of research that is still in its infancy. This review focuses on the impact of the intratumoral microbiota on cancer immune responses and highlights how the intratumoral microbiota modulates innate and adaptive immunity to potentially impact tumor immunotherapy in the hope that it will inspire potential ideas for the application of immunotherapy in the treatment of tumors.
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