严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)
大流行
生物
2019年冠状病毒病(COVID-19)
2019-20冠状病毒爆发
病毒学
病毒
结构生物学
疾病
传染病(医学专业)
细胞生物学
医学
病理
爆发
作者
Nathan Hardenbrook,Peijun Zhang
标识
DOI:10.1016/j.coviro.2021.11.011
摘要
The SARS-CoV-2 pandemic that struck in 2019 has left the world crippled with hundreds of millions of cases and millions of people dead. During this time, we have seen unprecedented support and collaboration amongst scientists to respond to this deadly disease. Advances in the field of structural biology, in particular cryoEM and cryo-electron tomography, have allowed unprecedented structural analysis of SARS-CoV-2. Here, we review the structural work on the SARS-CoV-2 virus and viral components, as well as its cellular assembly process, highlighting some important structural findings that have made significant impact on the protection from and treatment of emerging viral infections.
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