Protein-Protein Interaction (PPI) Network: Recent Advances in Drug Discovery

Background: The investigation of the cellular components, their interactions and related functions constitute the major conditions in order to understand the cell as an integrated system. More specifically, the Protein-Protein Interactions and the obtained networks are very important in the majority of biological functions and processes, while most of the proteins appear to activate their functionalities through their interaction. Keywords: Drug discovery, global network alignment, local network alignment, protein-protein interaction network, yeast two-hybrid system.