Enantioselective α-Hydrazination of α-Fluoro-β-Ketoesters Catalyzed by Bifunctional Organocatalysts

E-mail: dyoung@sch.ac.krReceived September 2, 2008Key Words : Bifunctional organocatalyst, Hydrazination, Asymmetric reactions, α-Fluoro-β-ketoesters Chiral organofluorine compounds containing a fluorineatom bonded directly to a stereogenic center have beenutilized in studies of enzyme mechanisms and as inter-mediates in asymmetric syntheses.