Methionine PET Findings in the Diagnosis of Brain Tumors and Nontumorous Mass Lesions: A Single-Center Report on 426 Cases

MET-PET demonstrated robust sensitivity for brain tumor detection but was limited by low specificity due to false-positives in inflammatory conditions and false-negatives for low-grade tumors. These findings imply the importance of integrating MET-PET with other imaging modalities to enhance diagnostic accuracy.