The role of astrocytes, circadian rhythms and light pollution in the pathogenesis of Alzheimer’s disease

Currently, more and more importance is being attached to the interaction of brain neurons with astrocytes in order to study the pathogenesis, and in the future, to develop methods for the prevention, early diagnosis and treatment of neurodegenerative diseases of the brain. In this review article, the authors attempt to demonstrate the role of astrocytes, disturbances in circadian rhythms, sleep-wake patterns, and light pollution in the development of Alzheimer's disease. Based on the analysis of literature data, possible mechanisms of synchronization and desynchronization of these processes are presented.