Depth Of Hydrogel Spacer Rectal Wall Infiltration (RWI) Was Not Associated With Rectal Toxicity: Results From A Randomized Prospective Trial

Rectal spacers have gained popularity as a dose-sparing material for prostate cancer radiation therapy (RT). However, the procedure can be associated with unintended rectal wall infiltration (RWI) of the spacer gel. We therefore classified RWI severity as a function of depth and explored its association with rectal toxicity using a data set from prostate cancer patients treated with RT on a prospective randomized clinical trial (RCT).