Eu3+-Doped Mixed-Ligand UiO-66-Type Metal–Organic Framework for Ratiometric Fluorescence Sensing Fluoride Ions with Ultralow Detection Limit

Metal-organic frameworks (MOFs) have emerged as a highly promising platform for various sensing applications due to their tunable structures and functionalities. In the present work, a Eu3+-doped mixed-ligand MOF, namely, the Eu3+@UiO-66-IPA, exhibited excellent luminescent properties and high fluorescence stability in aqueous media, displaying dual-emission peaks under 395 and 615 nm excitation that were readily visible to the naked eye. Importantly, the presence of fluoride ions (F-) promoted the "antenna effect" between the ligand and the Eu3+ centers, which significantly enhanced the emission intensity of the Eu3+ characteristic peak. In addition, the addition of F- also inhibited the quenching effect of high-energy O-H bonds existing in the aqueous environment. Notably, Eu3+@UiO-66-IPA demonstrated exceptional selectivity for F- over a range of competing anions, with a remarkable limit of detection as low as 0.22 μM. The developed Eu3+-doped mixed-ligand MOF system offers a highly promising strategy for the simple and accurate sensing of F- in practical applications.