Living probiotics-loaded wound matrices prepared by microchip electrospinning

in a 1 mm thick matrix. Using an agar overlay assay, it is determined that incorporated probiotics retain their functionality and antimicrobial activity against wound pathogens. This evidence confirms that the electrospun fibers containing microcapsules allow two-way diffusion of substances through pores in fibers (e.g., nutrients in, produced substances out) and support the viability of entrapped bacteria. The electrospun probiotics-loaded fiber matrix developed has potential to be used as a drug delivery system for wound infection treatment.