A general and selective Ni-catalysed reductive amination using hydrazine hydrate as facile hydrogen and nitrogen sources

Robust Ni-catalysed reductive amination of aldehydes/ketones with hydrazine hydrate yields primary amines (up to 99%). Enhanced reactivity and selectivity due to high Ni 0 ratio, small-sized Ni nanoparticles, and strong hydrazine nucleophilicity.