Direct Electrochemical Oxidation of NADPH at a Low Potential on the Carbon Nanotube Modified Glassy Carbon Electrode

Abstract NADPH can be directly oxidized on a carbon nanotube modified glassy carbon (CNT/GC) electrode in phosphate buffer solution (pH=6.0) with a diminution of the overpotential of more than 700 mV. The anodic peak currents increase linearly with the increase of concentration of NADPH in the range of 5×10 − ‐ 1 to 1×10 − ‐ 1 mom with a detection limit of about 1×10 − ‐ 1 mol/L. The CNT/GC electrode exhibits high sensitivity, low potential and stability in detecting NADPH and thus might be used in biosensors to study the electrocatalytic reaction of important de‐hydrogenase‐based biological systems.