医学
并发症
脑深部刺激
外科
死亡率
内科学
疾病
帕金森病
作者
Eun Jeong Koh,Joshua L Golubovsky,Richard Rammo,Arbaz Momin,Benjamin L. Walter,Hubert H. Fernández,André G. Machado,Sean J. Nagel
出处
期刊:Operative Neurosurgery
[Oxford University Press]
日期:2021-08-14
卷期号:21 (5): 277-290
被引量:7
摘要
Abstract BACKGROUND Deep brain stimulation (DBS) was first approved by the United States Food and Drug Administration in 1997. Although the fundamentals of DBS remain the same, hardware, software, and imaging have evolved significantly. OBJECTIVE To test our hypothesis that the aggregate complication rate in the medical literature in the past 12 years would be lower than what is often cited based on early experience with DBS surgery. METHODS PubMed, PsycINFO, and EMBASE were queried for studies from 2008 to 2020 that included patients treated with DBS from 2007 to 2019. This yielded 34 articles that evaluated all complications of DBS surgery, totaling 2249 patients. RESULTS The overall complication rate in this study was 16.7% per patient. There was found to be a systemic complication rate of 0.89%, intracranial complication rate of 2.7%, neurological complication rate of 4.6%, hardware complication rate of 2.2%, and surgical site complication rate of 3.4%. The infection and erosion rate was 3.0%. CONCLUSION This review suggests that surgical complication rates have decreased since the first decade after DBS was first FDA approved. Understanding how to minimize complications from the inception of a technique should receive more attention.
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