医学
长非编码RNA
伤口愈合
糖尿病
编码(社会科学)
临床意义
生物信息学
炎症
下调和上调
糖尿病神经病变
病理
外科
内科学
基因
内分泌学
生物
数学
统计
生物化学
作者
Le Kuai,Jingsi Jiang,Wei Li,Bin Li,Shuangyi Yin
摘要
Diabetic wounds are a protracted complication of diabetes mainly characterised by chronic inflammation, obstruction of epithelialization, damaged blood vessels and collagen production (maturation), as well as neuropathy. As a non-coding RNA (ncRNA) that lack coding potential, long non-coding RNAs (lncRNAs) have recently been reported to play a salient role in diabetic wound healing. Here, this review summarises the roles of lncRNAs in the pathology and treatments of diabetic wounds, providing references for its potential clinical diagnostic criteria or therapeutic targets in the future.
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