银屑病
医学
最后
表皮系统
特应性皮炎
皮肤病科
不利影响
病理
内科学
银屑病性关节炎
作者
Lauren Valentine,Matthew Norris,Leonard Bielory
出处
期刊:Current Opinion in Allergy and Clinical Immunology
[Ovid Technologies (Wolters Kluwer)]
日期:2021-08-12
卷期号:21 (5): 472-479
被引量:3
标识
DOI:10.1097/aci.0000000000000775
摘要
The purpose of this review is to highlight and compare the structural and functional differences between the ocular surface and the skin. The goal is to further understand how these components interact from an immunobiological standpoint, which may inform future therapeutic uses.Treatment agents, such as Dupilumab and Apremilast are traditionally indicated for integumentary conditions, such as atopic dermatitis and psoriasis, respectively. Both were also found to have potent effects on the conjunctival surface and ocular glands, which may be attributed to the similarities in structure.Surfaces of the eyes and the skin are found to have similar composition in terms of immunohistology, steroidogenic properties, and allergic mechanisms. These translate directly into both the adverse effects and therapeutic benefits that overlap when treating these surfaces.
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