喷墨打印
纳米技术
3D生物打印
脚手架
计算机科学
工程类
墨水池
组织工程
生物医学工程
语音识别
材料科学
作者
Xinda Li,Boxun Liu,Ben Pei,Jianwei Chen,Dezhi Zhou,Jiayi Peng,Xinzhi Zhang,Wang Jia,Tao Xu
出处
期刊:Chemical Reviews
[American Chemical Society]
日期:2020-09-09
卷期号:120 (19): 10793-10833
被引量:362
标识
DOI:10.1021/acs.chemrev.0c00008
摘要
The inkjet technique has the capability of generating droplets in the picoliter volume range, firing thousands of times in a few seconds and printing in the noncontact manner. Since its emergence, inkjet technology has been widely utilized in the publishing industry for printing of text and pictures. As the technology developed, its applications have been expanded from two-dimensional (2D) to three-dimensional (3D) and even used to fabricate components of electronic devices. At the end of the twentieth century, researchers were aware of the potential value of this technology in life sciences and tissue engineering because its picoliter-level printing unit is suitable for depositing biological components. Currently inkjet technology has been becoming a practical tool in modern medicine serving for drug development, scaffold building, and cell depositing. In this article, we first review the history, principles and different methods of developing this technology. Next, we focus on the recent achievements of inkjet printing in the biological field. Inkjet bioprinting of generic biomaterials, biomacromolecules, DNAs, and cells and their major applications are introduced in order of increasing complexity. The current limitations/challenges and corresponding solutions of this technology are also discussed. A new concept, biopixels, is put forward with a combination of the key characteristics of inkjet printing and basic biological units to bring a comprehensive view on inkjet-based bioprinting. Finally, a roadmap of the entire 3D bioprinting is depicted at the end of this review article, clearly demonstrating the past, present, and future of 3D bioprinting and our current progress in this field.
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